Article Abstract

High-risk atherosclerotic plaque features for cardiovascular risk assessment in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain trial

Authors: Subhi J. Al’Aref, Jessica M. Peña, James K. Min


Over the past decade, our understanding of coronary atherosclerosis has evolved from a paradigm dominated by coronary stenosis towards a deeper, more nuanced appreciation of coronary anatomy and physiology. Following the observation that most myocardial infarctions are caused by lesions deemed non-obstructive, there has been continued fervent search for imaging markers of plaque likely to cause adverse events.