Right Ventricular Dysfunction

Posted On 2020-11-10 15:45:28


This series on “Right Ventricular Dysfunction” is edited by:
- Martin Koestenberger, Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Graz, Austria; European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany;
- Harm-Jan Bogaard, Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands; and
- Georg Hansmann, European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany; Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

In the last decades, substantial progress has been made in the diagnosis and treatment of right ventricular dysfunction in pediatric and adult patients. The pathobiology of right ventricular dysfunction, however, is heterogenous and broad, and, thus, there are many obstacles and areas of uncertainties to unpack. In this special issue, internationally renowned experts from multiple specialties comprehensively discuss impactful discoveries and innovations in the fascinating field of RV dysfunction that have emerged in the last years, both in adult and the pediatric disciplines.

Editorial on Right Ventricular Dysfunction
Getting to the bottom of right heart failure
Martin Koestenberger, Harm-Jan Bogaard, Georg Hansmann

Review Article on Right Ventricular Dysfunction
Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid metabolism
Vineet Agrawal, Tim Lahm, Georg Hansmann, Anna R. Hemnes

Left ventricular dysfunction in heart failure with preserved ejection fraction—molecular mechanisms and impact on right ventricular function
Frank R. Heinzel, Niklas Hegemann, Felix Hohendanner, Uwe Primessnig, Jana Grune, Florian Blaschke, Rudolf A. de Boer, Burkert Pieske, Gabriele G. Schiattarella, Wolfgang M. Kuebler

Animal models of right heart failure
Asger Andersen, Diederik E. van der Feen, Stine Andersen, Jacob Gammelgaard Schultz, Georg Hansmann, Harm Jan Bogaard

Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction
Roberto J. Bernardo, Francois Haddad, Etienne J. Couture, Georg Hansmann, Vinicio A. de Jesus Perez, André Y. Denault, Frances S. de Man, Myriam Amsallem

Update on noninvasive imaging of right ventricle dysfunction in pulmonary hypertension
Uyen Truong, Katharina Meinel, Francois Haddad, Martin Koestenberger, Jørn Carlsen, Dunbar Ivy, Pei-Ni Jone

Diagnosis and treatment of right ventricular dysfunction in congenital heart disease
Béatrice Santens, Alexander Van De Bruaene, Pieter De Meester, Michele D’Alto, Sushma Reddy, Daniel Bernstein, Martin Koestenberger, Georg Hansmann, Werner Budts

Right ventricular dysfunction and long-term risk of death
Jason L. Sanders, Martin Koestenberger, Stephan Rosenkranz, Bradley A. Maron

Treatment of right ventricular dysfunction and heart failure in pulmonary arterial hypertension
Chakradhari Inampudi, Ryan J. Tedford, Anna R. Hemnes, Georg Hansmann, Harm-Jan Bogaard, Martin Koestenberger, Irene Marthe Lang, Evan L. Brittain

Original Article on Right Ventricular Dysfunction
Safety and efficacy of the endothelin receptor antagonist macitentan in pediatric pulmonary hypertension
Sabrina Schweintzger, Martin Koestenberger, Axel Schlagenhauf, Gernot Grangl, Ante Burmas, Stefan Kurath-Koller, Mirjam Pocivalnik, Hannes Sallmon, Daniela Baumgartner, Georg Hansmann, Andreas Gamillscheg

Case Report on Right Ventricular Dysfunction
Mineralocorticoid receptor blockade improves pulmonary hypertension and right ventricular function in bronchopulmonary dysplasia: a case report
Roberto Giagnorio, Georg Hansmann

Prenatal duct closure leading to severe pulmonary hypertension in a preterm neonate—a case report
Anna M. Bakas, Helen M. Healy, Katherine A. Bell, David W. Brown, Mary Mullen, Annette Scheid

Interventional creation of an endogenous reverse Potts shunt in an infant with pulmonary hypertension and genetic surfactant disorder—a case report
Hannes Sallmon, Felix Berger, Sven C. Weber, Hendrik S. Fischer, Georg Hansmann, Bernd Opgen-Rhein

Review Article on Right Ventricular Dysfunction
Cardiac multi-scale investigation of the right and left ventricle ex vivo: a review
Hector Dejea, Anne Bonnin, Andrew C. Cook, Patricia Garcia-Canadilla

Editorial Commentary on Right Ventricular Dysfunction
Cardiac catheterization in pulmonary hypertension: doing it right, with a catheter on the left
Georg Hansmann, Stuart Rich, Bradley A. Maron

Peri-operative right ventricular dysfunction—the anesthesiologist’s view
Manchula Navaratnam, James A. DiNardo

Review Article on Right Ventricular Dysfunction
Emerging therapies for right ventricular dysfunction and failure
Anna Klinke, Torben Schubert, Marion Müller, Ekaterina Legchenko, Jason G. E. Zelt, Tsukasa Shimauchi, L. Christian Napp, Alexander M. K. Rothman, Sébastien Bonnet, Duncan J. Stewart, Georg Hansmann, Volker Rudolph


Disclosure:
The focused issue “Right Ventricular Dysfunction” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding. Martin Koestenberger, Harm Jan Bogaard and Georg Hansmann are serving as the unpaid Guest Editors for the focused issue.