TY - JOUR AU - Liu, Tong AU - Korantzopoulos, Panagiotis AU - Li, Guangping PY - 2012 TI - Antioxidant therapies for the management of atrial fibrillation JF - Cardiovascular Diagnosis and Therapy; Vol 2, No 4 (December 18, 2012): Cardiovascular Diagnosis and Therapy Y2 - 2012 KW - N2 - Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, representing a major public health problem. Recent evidence suggests oxidative stress may play an important role in the pathogenesis and perpetuation of AF. In the past few years, experimental data and clinical evidence have tested the concept of antioxidant therapies to prevent AF. Besides statins, ACE-inhibitors (ACEIs) and/or angiotensin-receptor blockers (ARBs), and omega-3 polyunsaturated fatty acids, several other interventions with antioxidant properties, such as Vitamin C and E, thiazolidinediones, N-acetylcysteine, probucol, nitric oxide donors or precursors, NADPH oxidase inhibitors, Xanthine oxidase inhibitors have emerged as novel strategies for the management of AF. We aim to review recent evidence regarding antioxidant therapies in the prevention and treatment of atrial fibrillation. UR - https://cdt.amegroups.org/article/view/1288