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Infective endocarditis in South Africa

  
@article{CDT26995,
	author = {Alfonso Jan Pecoraro and Anton Frans Doubell},
	title = {Infective endocarditis in South Africa},
	journal = {Cardiovascular Diagnosis and Therapy},
	volume = {0},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Infective endocarditis (IE) is defined by infection of either a native or prosthetic heart valve, endocardial surface or any cardiac prosthetic device. It is a disease of both the developed and developing world, although IE has evolved in the developed world to a disease markedly different to the disease encountered in the developing world. IE in developed nations is mainly a disease of older patients with degenerative heart valve disease or cardiac prosthetic material, with virulent Staphylococci the most common causative organism. Data regarding the epidemiology of IE in South Africa, a developing country, is limited. The available data suggest it is still a disease of younger patients with rheumatic heart disease (RHD), associated with penicillin-sensitive Streptococcal infection. Although novel diagnostic techniques and improved therapeutic options has emerged, the 1-year mortality rate has remained high in both the developed and developing world at around 30%.},
	issn = {2223-3660},	url = {http://cdt.amegroups.com/article/view/26995}
}