This series on “Right Ventricular Dysfunction” is edited by:
- Martin Koestenberger, Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Graz, Austria; European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany;
- Harm-Jan Bogaard, Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands; and
- Georg Hansmann, European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany; Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.
In the last decades, substantial progress has been made in the diagnosis and treatment of right ventricular dysfunction in pediatric and adult patients. The pathobiology of right ventricular dysfunction, however, is heterogenous and broad, and, thus, there are many obstacles and areas of uncertainties to unpack. In this special issue, internationally renowned experts from multiple specialties comprehensively discuss impactful discoveries and innovations in the fascinating field of RV dysfunction that have emerged in the last years, both in adult and the pediatric disciplines.
Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid metabolism
Left ventricular dysfunction in heart failure with preserved ejection fraction—molecular mechanisms and impact on right ventricular function
Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction
Safety and efficacy of the endothelin receptor antagonist macitentan in pediatric pulmonary hypertension
Mineralocorticoid receptor blockade improves pulmonary hypertension and right ventricular function in bronchopulmonary dysplasia: a case report
Interventional creation of an endogenous reverse Potts shunt in an infant with pulmonary hypertension and genetic surfactant disorder—a case report
The focused issue “Right Ventricular Dysfunction” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding. Martin Koestenberger, Harm Jan Bogaard and Georg Hansmann served as the unpaid Guest Editors for the focused issue.