TY - JOUR AU - De Stefano, Luciano AU - de Arenaza, Diego Perez AU - Yeyati, Ezequiel Levy AU - Pietrani, Marcelo AU - Kohan, Andres AU - Falconi, Mariano AU - Benger, Juan AU - Dragonetti, Laura AU - Garcia-Monaco, Ricardo AU - Cagide, Arturo PY - 2014 TI - Low rate of cardiovascular events in patients with acute myocarditis diagnosed by cardiovascular magnetic resonance JF - Cardiovascular Diagnosis and Therapy; Vol 4, No 2 (April 23, 2014): Cardiovascular Diagnosis and Therapy (MR Imaging in Cardiovascular Disease) Y2 - 2014 KW - N2 - Background: Myocarditis is a relatively common inflammatory disease that affects the myocardium. Infectious disease accounts for most of the cases either because of a direct viral infection or post-viral immune-mediated reaction. Cardiovascular magnetic resonance (CMR) has become an established non-invasive diagnosis tool for acute myocarditis. A recent large single centre study with patients with biopsy-proven viral myocarditis undergoing CMR scans found a high rate of mortality. The aim of this study was to assess the rate of clinical events in our population of patients with diagnosed myocarditis by CMR scan. Methods: Patients who consulted to the emergency department with diagnosis of myocarditis by CMR were retrospectively included in the study from January 2008 to May 2012. A CMR protocol was used in all patients, and were followed up to assess the rate of the composite endpoint of all-cause death, congestive heart failure, sudden cardiac death, hospitalization for cardiac cause, recurrent myocarditis or need of radiofrequency ablation or implantable cardiac defibrillator (ICD). A descriptive statistical analysis was performed. Results: Thirty-two patients with myocarditis were included in the study. The mean age was 42.6±21.2 years and 81.2% were male. In a mean follow up of 30.4±17.8 months, the rate of the composite endpoint of all-cause death, congestive heart failure, sudden cardiac death, hospitalization for cardiac cause, recurrent myocarditis or need of radiofrequency ablation or ICD was 15.6% (n=5). Two patients had heart failure (one of them underwent heart transplant), one patient needed ICD because of ventricular tachycardia and two other patients were re-hospitalized, for recurrent chest pain and for recurrent myocarditis respectively. Conclusions: In our series of acute myocarditis diagnosed by CMR we found a low rate of cardiovascular events without mortality. These findings might oppose data from recently published myocarditis trials. UR - https://cdt.amegroups.org/article/view/3565