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减盐奋斗中的进展与挑战

阐述了世界不同国家为了减少盐摄入而做出的努力…… More >>

中国减少盐摄入与高血压的研究现状与展望

高血压及其导致的脑卒中、心力衰竭等是一个严重的公共健康问题。 More >>

澳大利亚减少食盐摄入:从倡议到行动

澳大利亚联邦政府已经承诺到2025年人均食盐摄入量减少30%…… More >>

Arts and Medicine more

Installations, video works, paintings More >>
Networked Life More >>
Dimension of time in strange attractors More >>

Original Article

MicroRNA-221 promotes proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) by targeting tissue inhibitor of metalloproteinases-3 (TIMP3)
Yan Yan, Ying Xu, Gehui Ni, Siqi Wang, Xinli Li, Juan Gao, Haifeng Zhang
Inhibition of ERK or Akt ameliorates intimal hyperplasia via up-regulation of Cx37 and down-regulation of Cx43 in balloon injury rat model
Lemen Pan, Haizhen Ni, Wenxu Jin, Xiang Su
Incidence of myocardial injury in coronavirus disease 2019 (COVID-19): a pooled analysis of 7,679 patients from 53 studies
Zhi-Chun Gu, Chi Zhang, Ling-Cong Kong, Long Shen, Zheng Li, Heng Ge, Hou-Wen Lin, Jun Pu
Analysis of influencing factors related to elevated serum troponin I level for COVID-19 patients in Yichang, China
Zhi-Xing Fan, Jun Yang, Jing Zhang, Chao He, Hui Wu, Chao-Jun Yang, Tao Zheng, Cong Ma, Zu-Jin Xiang, Yu-Hong Zhai, Jing Jiang, Shao-Qin Qiu, Jian Yang
MicroRNA-374 is a potential diagnostic biomarker for atherosclerosis and regulates the proliferation and migration of vascular smooth muscle cells
Weihong Wang, Fenghua Ma, Hongyan Zhang
Exogenous endothelial progenitor cells reached the deficient region of acute cerebral ischemia rats to improve functional recovery via Bcl-2
Yan Hong, Qing Yu, Zhaohong Kong, Meiyao Wang, Renwei Zhang, Yan Li, Yumin Liu
Diminished response to statins predicts the occurrence of heart failure after acute myocardial infarction
Kosuke Tsuda, Yu Kataoka, Soshiro Ogata, Kunihiro Nishimura, Ryo Nishikawa, Takahito Doi, Takahiro Nakashima, Hayato Hosoda, Satoshi Honda, Shoji Kawakami, Masashi Fujino, Kazuhiro Nakao, Shuichi Yoneda, Kensaku Nishihira, Fumiyuki Otsuka, Yoshio Tahara, Yasuhide Asaumi, Masaaki Hoshiga, Teruo Noguchi, Satoshi Yasuda
Prevalence and risk factors of left atrial thrombus in patients with atrial fibrillation and lower class (IIa) recommendation to anticoagulants
Beata Uziębło-Życzkowska, Paweł Krzesiński, Agnieszka Jurek, Monika Budnik, Iwona Gorczyca, Agnieszka Kapłon-Cieślicka, Marek Kiliszek, Agnieszka Wójcik, Monika Gawałko, Olga Jelonek, Anna Michalska, Katarzyna Starzyk, Piotr Scisło, Janusz Kochanowski, Krzysztof J. Filipiak, Beata Wożakowska-Kapłon, Grzegorz Opolski, Grzegorz Gielerak
Performance of cardiovascular magnetic resonance strain in patients with acute myocarditis
Xiaorong Chen, Hongjie Hu, Jiangfeng Pan, Jiner Shu, Yi Hu, Risheng Yu
Hypermethylation of miR-181b in monocytes is associated with coronary artery disease and promotes M1 polarized phenotype via PIAS1-KLF4 axis
Zhonghua Wang, Chunlei Li, Xinyong Sun, Zhuqin Li, Jia Li, Lanfeng Wang, Yanming Sun
Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner
Wei Yu, Xing Qin, Yuchen Zhang, Peng Qiu, Linge Wang, Wenliang Zha, Jun Ren
Nomogram developed with selenoprotein S (SelS) genetic variation and clinical characteristics predicting risk of coronary artery disease in a Chinese population
Ding-Yu Wang, Ting-Ting Wu, Ying-Ying Zheng, Yi-Tong Ma, Xiang Xie
Ephrin B2 mediates high glucose induced endothelial-to-mesenchymal transition in human aortic endothelial cells
Cheng Yuan, Lihua Ni, Changjiang Zhang, Hao Xia, Xiaoyan Wu
Are dilated ascending aortas of Chinese patients more likely to dissect?
Wenjian Jiang, Jihong Liu, Lu Dai, Yang Liu, Zining Wu, Hongjia Zhang
Study on the mechanism of anti-MIRI action of total flavones of Fructus Chorspondiatis by PET/CT imaging
Guo-Jian Zhang, Li-Hong Wei, Hai-Wen Lu, Yun-Feng Xiao, Wen-Rui Wang, Yu-Lin He, Xue-Mei Wang, Jia-He Tian
Downregulation of long noncoding RNA SNHG6 rescued propofol-induced cytotoxicity in human induced pluripotent stem cell-derived cardiomyocytes
Zhongguo Ren, Rong Hu
Machine learning-based CT fractional flow reserve assessment in acute chest pain: first experience
Matthias Eberhard, Tin Nadarevic, Andrej Cousin, Jochen von Spiczak, Ricarda Hinzpeter, Andre Euler, Fabian Morsbach, Robert Manka, Dagmar I. Keller, Hatem Alkadhi
Effectiveness of magnetocardiography to identify patients in need of coronary artery revascularization: a cross-sectional study
Xiao Huang, Ning Hua, Fakuan Tang, Shulin Zhang
Early clinical outcomes of thoracoscopic mitral valvuloplasty: a clinical experience of 100 consecutive cases
Huimin Cui, Lin Zhang, Shixiong Wei, Lianggang Li, Tong Ren, Yao Wang, Shengli Jiang
MiR-181c protects cardiomyocyte injury by preventing cell apoptosis through PI3K/Akt signaling pathway
Xiaoli Li, Jiuchang Zhong, Zhen Zeng, Hongjiang Wang, Jing Li, Xiaoyan Liu, Xinchun Yang
A comparison of artificial intelligence-based algorithms for the identification of patients with depressed right ventricular function from 2-dimentional echocardiography parameters and clinical features
Ali Ahmad, Zahi Ibrahim, Georges Sakr, Abdallah El-Bizri, Lara Masri, Imad H. Elhajj, Nehme El-Hachem, Hussain Isma’eel

Original Article on Advanced Imaging in The Diagnosis of Cardiovascular Diseases1

Cardiovascular/stroke risk predictive calculators: a comparison between statistical and machine learning models
Ankush Jamthikar, Deep Gupta, Luca Saba, Narendra N. Khanna, Tadashi Araki, Klaudija Viskovic, Sophie Mavrogeni, John R. Laird, Gyan Pareek, Martin Miner, Petros P. Sfikakis, Athanasios Protogerou, Vijay Viswanathan, Aditya Sharma, Andrew Nicolaides, George D. Kitas, Jasjit S. Suri
Ultrasound-based stroke/cardiovascular risk stratification using Framingham Risk Score and ASCVD Risk Score based on “Integrated Vascular Age” instead of “Chronological Age”: a multi-ethnic study of Asian Indian, Caucasian, and Japanese cohorts
Ankush Jamthikar, Deep Gupta, Elisa Cuadrado-Godia, Anudeep Puvvula, Narendra N. Khanna, Luca Saba, Klaudija Viskovic, Sophie Mavrogeni, Monika Turk, John R. Laird, Gyan Pareek, Martin Miner, Petros P. Sfikakis, Athanasios Protogerou, George D. Kitas, Chithra Shankar, Andrew Nicolaides, Vijay Viswanathan, Aditya Sharma, Jasjit S. Suri

Review Article on Advanced Imaging in The Diagnosis of Cardiovascular Diseases1

Uses of ultrasound in stroke prevention
J. David Spence
Contrast imaging ultrasound for the detection and characterization of carotid vulnerable plaque
Vasileios Rafailidis, Xin Li, Paul S. Sidhu, Sasan Partovi, Daniel Staub
Vessel wall MR imaging of intracranial atherosclerosis
Jae W. Song, Bruce A. Wasserman
Imaging of intracranial atherosclerotic plaques using 3.0 T and 7.0 T magnetic resonance imaging—current trends and future perspectives
Fang Wu, Huan Yu, Qi Yang
Carotid plaque imaging profiling in subjects with risk factors (diabetes and hypertension)
Michele Porcu, Lorenzo Mannelli, Marta Melis, Jasjit S. Suri, Clara Gerosa, Giulia Cerrone, Giovanni Defazio, Gavino Faa, Luca Saba
MR imaging of vulnerable carotid plaque
Michael E. Porambo, J. Kevin DeMarco
Plaque imaging volume analysis: technique and application
Alessandro Murgia, Antonella Balestrieri, Marco Francone, Pierleone Lucatelli, Elisa Scapin, Andrew Buckler, Giulio Micheletti, Gavino Faa, Maurizio Conti, Jasjit S. Suri, Giuseppe Guglielmi, Alessandro Carriero, Luca Saba
Carotid plaque imaging and the risk of atherosclerotic cardiovascular disease
Guangming Zhu, Jason Hom, Ying Li, Bin Jiang, Fatima Rodriguez, Dominik Fleischmann, David Saloner, Michele Porcu, Yanrong Zhang, Luca Saba, Max Wintermark
4D flow imaging of the thoracic aorta: is there an added clinical value?
Federica Catapano, Giacomo Pambianchi, Giulia Cundari, João Rebelo, Francesco Cilia, Iacopo Carbone, Carlo Catalano, Marco Francone, Nicola Galea
Dual-energy CT and coronary imaging
Fernando Uliana Kay
Vessel wall MR imaging for the detection of intracranial inflammatory vasculopathies
Myriam Edjlali, Ye Qiao, Gregoire Boulouis, Nicolas Menjot, Luca Saba, Bruce Alan Wasserman, Javier M. Romero
PET/MRI of atherosclerosis
Mueez Aizaz, Rik P. M. Moonen, Jochem A. J. van der Pol, Claudia Prieto, René M. Botnar, M. Eline Kooi
Heart applications of 4D flow
Giuseppe Corrias, Daniele Cocco, Jasjit S. Suri, Luigi Meloni, Filippo Cademartiri, Luca Saba
Insight from imaging on plaque vulnerability: similarities and differences between coronary and carotid arteries—implications for systemic therapies
Filippo Cademartiri, Antonella Balestrieri, Riccardo Cau, Bruna Punzo, Carlo Cavaliere, Erica Maffei, Luca Saba

Disclosure:

1. The series “Advanced Imaging in The Diagnosis of Cardiovascular Diseases” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding. Luca Saba served as the unpaid Guest Editor for the series.

2. The series “Arts and Medicine” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding.

Original Article

Risk factors of prolonged mechanical ventilation following open heart surgery: what has changed over the last decade?
Muhammad-Mujtaba Ali Siddiqui, Iftikhar Paras, Anjum Jalal

Case Report

Kounis syndrome - an atopic monster for the heart
Venkataramanan Gangadharan, Samit Bhatheja, Kais Al Balbissi

Original Article

Reproducibility of myocardial perfusion reserve - variations in measurements from post processing using commercially available software
Pavel Goykhman, Puja K. Mehta, Megha Agarwal, Chrisandra Shufelt, Piotr J. Slomka, Yuching Yang, Yuan Xu, Leslee J. Shaw, Daniel S. Berman, Noel Bairey Merz, Louise E. J. Thomson
3D morphometry using automated aortic segmentation in native MR angiography: an alternative to contrast enhanced MRA?
Matthias Müller-Eschner, Tobias Müller, Andreas Biesdorf, Stefan Wörz, Fabian Rengier, Dittmar Böckler, Hans-Ulrich Kauczor, Karl Rohr, Hendrik von Tengg-Kobligk
Noninvasive pressure difference mapping derived from 4D flow MRI in patients with unrepaired and repaired aortic coarctation
Fabian Rengier, Michael Delles, Joachim Eichhorn, Yoo-Jin Azad, Hendrik von Tengg-Kobligk, Julia Ley-Zaporozhan, Rüdiger Dillmann, Hans-Ulrich Kauczor, Roland Unterhinninghofen, Sebastian Ley
Life span of patients with Eisenmenger syndrome is not superior to that of patients with other causes of pulmonary hypertension
Béatrice Bonello, Sébastien Renard, Julien Mancini, Sandrine Huber, Gilbert Habib, Alain Fraisse
Vegetarian diets and glycemic control in diabetes: a systematic review and meta-analysis
Yoko Yokoyama, Neal D. Barnard, Susan M. Levin, Mitsuhiro Watanabe

Review Article

Hypoxamirs in pulmonary hypertension: breathing new life into pulmonary vascular research
Andrew E. Hale, Kevin White, Stephen Y. Chan
Bone marrow-derived cell therapy in chagasic cardiac disease: a review of pre-clinical and clinical results
Antonio Carlos Campos de Carvalho, Adriana Bastos Carvalho, Debora Bastos Mello, Regina Coeli dos Santos Goldenberg
Imaging in the context of replacement heart valve development: Use of the Visible Heart® methodologies
Michael G. Bateman, Paul A. Iaizzo
Antioxidant therapies for the management of atrial fibrillation
Tong Liu, Panagiotis Korantzopoulos, Guangping Li
The Popeye domain containing genes: essential elements in heart rate control
Roland F. Schindler, Kar Lai Poon, Subreena Simrick, Thomas Brand
Dynamic contrast-enhanced magnetic resonance imaging: fundamentals and application to the evaluation of the peripheral perfusion
Yaron Gordon, Sasan Partovi, Matthias Müller-Eschner, Erik Amarteifio, Tobias Bäuerle, Marc-André Weber, Hans-Ulrich Kauczor, Fabian Rengier
4D flow imaging with MRI
Zoran Stankovic, Bradley D. Allen, Julio Garcia, Kelly B. Jarvis, Michael Markl
Review of MRI-based measurements of pulse wave velocity: a biomarker of arterial stiffness
Andrew L. Wentland, Thomas M. Grist, Oliver Wieben

Brief Report

Correlates of objectively measured physical activity in cardiac patients
Wonwoo Byun, Cemal Ozemek, Katrina Riggin, Scott Strath, Leonard Kaminsky

Original Articles

Left ventricular energy model predicts adverse events in women with suspected myocardial ischemia: results from the NHLBI-sponsored women’s ischemia syndrome evaluation (WISE) study
Mark Doyle, Nicole Weinberg, Gerald M. Pohost, C. Noel Bairey Merz, Leslee J. Shaw, George Sopko, Anthon Fuisz, William J. Rogers, Edward G. Walsh, B. Delia Johnson, Barry L. Sharaf, Carl J. Pepine, Sunil Mankad, Steven E. Reis, Geetha Rayarao, Diane A. Vido, Vera Bittner, Lindsey Tauxe, Marian B. Olson, Sheryl F. Kelsey, Robert WW Biederman
Cardiac risk factors and myocardial perfusion reserve in women with microvascular coronary dysfunction
Megha Agarwal, Chrisandra Shufelt, Puja K. Mehta, Edward Gill, Daniel S. Berman, Debiao Li, Behzad Sharif, Ning Li, C. Noel Bairey Merz, Louise E.J. Thomson
Cardiac magnetic resonance imaging myocardial perfusion reserve index assessment in women with microvascular coronary dysfunction and reference controls
Chrisandra L. Shufelt, Louise E. J. Thomson, Pavel Goykhman, Megha Agarwal, Puja K. Mehta, Tara Sedlak, Ning Li, Edward Gill, Bruce Samuels, Babak Azabal, Saibal Kar, Kamlesh Kothawade, Margo Minissian, Piotr Slomka, Daniel S. Berman, C. Noel Bairey Merz
Improved diagnosis and prognosis using Decisions Informed by Combining Entities (DICE): results from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE)
Mark Doyle, Gerald M. Pohost, C. Noel Bairey Merz, Leslee J. Shaw, George Sopko, William J. Rogers, Barry L. Sharaf, Carl J. Pepine, Diane A. Vido-Thompson, Geetha Rayarao, Lindsey Tauxe, Sheryl F. Kelsey, Douglas Mc Nair, Robert W. Biederman

The following articles are published ahead of print.

Arts and Medicine




Case Report


Original Article


Review Article

May-Thurner syndrome
Santhosh Poyyamoli, Pankaj Mehta, Mathew Cherian, Rinoy R. Anand, Santosh B. Patil, Sanjeeva Kalva, Gloria Salazar


Arts and Medicine